CINCINNATI (AP) - Sammy Sosa again came up empty in his quest for homer No. 60, but Henry Rodriguez hit his first in nearly a month as the Chicago Cubs beat the Cincinnati Reds 4-3 Tuesday night.

Sosa failed to get the ball out of the infield against Pete Harnisch (14-9), then completed an 0-for-4 night with a groundout in the ninth against Dennys Reyes, who gave up Mark McGwire's 60th homer last year.

Rodriguez's solo homer to center field, his first since Aug. 18, broke a seventh-inning tie and ended the Reds' seven-game winning streak. Jose Nieves added a two-run triple in the ninth.

The Reds had won 10 of their 11 previous games and began the night three games behind Houston in the NL Central and 2 1/2 games back of New York in the wild-card race.

Chicago, which has two fewer wins than Sosa has home runs, ended its six-game losing streak with only its ninth victory in 43 games since Aug. 1.

Kyle Farnsworth (4-9) gave up only three hits in six innings, including Barry Larkin's solo homer, to get his first victory in three starts this month.

Rick Aguilera got out of a two-on, one-out threat in the eighth when Eddie Taubensee struck out and rookie Kerry Robinson was thrown out trying to steal third on the pitch. Terry Adams pitched the ninth for his 13th save in 16 chances, allowing Jeffrey Hammonds' first career pinch-homer, a two-run, two-out shot. With two on, Dmitri Young hit a game-ending grounder.

A crowd of 23,353 that came to see Sosa swing away for No. 60 instead watched the Reds get their 1,000th loss to the Cubs.

Sosa, who last year became the fourth player to hit 60 homers in a season, is trying to become the first to do it twice. He hasn't homered in 19 at-bats since last Thursday.

He got loud ovations and dozens of flashbulbs went off throughout the half-filled stadium every time Sosa came to bat. He struck out swinging in the first, shattered his bat on a groundout in the fourth and lined out to third baseman Aaron Boone in the sixth before grounding out in the ninth.

The first three at-bats were against Harnisch, who gave up homer No. 59 five days earlier in Chicago. Harnisch is having one of his finest seasons, but is 0-2 in four starts against the Cubs.

Sosa wasn't the only one having trouble hitting the ball. Harnisch and Farnsworth held down the offenses to three hits apiece before the bullpens came into play.

Larkin, who went a career-record 72 games without a homer before breaking the streak last Friday, hit another in the bottom of the first to put the Reds ahead 1-0.

The Cubs tied it with their first hit in the third inning off Harnisch, who walked Jose Nieves with one out. Farnsworth had a sacrifice bunt and Lance Johnson singled to left to tie it.

Farnsworth got a double-play from Taubensee to hinder a two-on, none-out threat in the fourth, and got Boone to ground out with runners on second and third in the sixth.

Pirates fall to Diamondbacks

PHOENIX (AP) - Hanley Frias singled and scored the winning run on Pittsburgh first baseman Kevin Young's fielding error, and the Arizona Diamondbacks beat the Pirates 2-1 Tuesday night.

Erubiel Durazo had a solo homer and a single in three at-bats for the Diamondbacks, who reduced their magic number to 10.

Mark Wilkins (2-3) gave up Frias' hit and one unearned in the ninth.

Brian Anderson, in his first start in four weeks because of manager Buck Showalter's decision to rest Armando Reynoso, allowed one hit and two walks, and struck out two in his seven-inning stint that ran his scoreless-inning string to 16.

In his last start before being sent to the bullpen to make room for Todd Stottlemyre's return from the disabled list, Anderson threw a three-hit shutout against the Chicago Cubs.

But Anderson came out after throwing 77 pitches through seven innings, and reliever Gregg Olson gave up a solo homer to pinch-hitter Brant Brown in the eighth, followed by a double by Dale Sveum.

Matt Mantei picked up his 29th save in 33 opportunities, striking out the last two batters with runners on second and third.